Dysregulation of urate transporters in the proximal convoluted tubule constitutes the principal determinant of net urinary excretion (Nakayama et al., 2023
304306 The diversity of signals collectively detected by MerR sensors may well be broader than that of the ArsR family as they not only form coordination complexes with monovalent and divalent metal ions, e.g., mercury (Hg), 135,307,308 cadmium (Cd), 309,310 lead, 237,311 cobalt, 312 zinc, 313 iron, 314 nickel, 315 gold (Au I ) 304,316 and copper, 317 but also respond to oxidative stressors, 305,318 carbonyl and nitrosative stressors, 319,320 and lipophilic drug molecules 306,321 (Figure 11A)
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Neurology 2004
Chen X, Xie C, Sun L, Ding J, Cai H